ESC Textbook of Cardiovascular Medicine

ESC Textbook of Cardiovascular Medicine

Oxford University Press ESC logo
 

Symbols and abbreviations

E
cross reference
Formula
additional online material
Formula
website
(e)NOS
(endothelial) nitric oxide synthase
2D
two-dimensional
3D
three-dimensional
AACVPR
American Association of Cardiovascular Prevention and Rehabilitation
ABCD
Appropriate Blood pressure Control in Diabetes
ACC
American College of Cardiology
ACCP
American College of Chest Physicians
ACE
angiotensin-converting enzyme
ACEI
angiotensin-converting enzyme inhibitor
ACM
all-cause mortality or alcoholic cardiomyopathy
ACT
activated coagulation time
ADA
American Diabetes Association
ADH
antidiuretic hormone
ADP
adenosine diphosphate
AED
automated external defibrillator
AF
atrial fibrillation
AGE
advanced glycation end-product
AH
atrial–His
AHA
American Heart Association
ALAT
alanine amino transferase
ALT
alanine aminotransferase
AMDG
airport metal detector gates
AMI
acute myocardial infarction
ANP
atrial natriuretic peptide
Ao
aorta
AoA
aortic orifice area
apoB
apolipoprotein B
apoE
apolipoprotein E
aPTT
activated partial thromboplastin time
AR
aortic regurgitation
ARB
angiotensin receptor blocker
ARR
absolute risk reduction
ART
assisted reproductive technology
ARVC
arrhythmogenic right ventricular cardiomyopathy
AS
aortic stenosis
ASA
acetylsalicylic acid
AST
aspartate aminotransferase
ASD
atrial septal defect
ASF
anterosuperior fascicle
AST
aspartate aminotransferase
ATP
adenosine triphosphate
AV
atrioventricular
AVA
aortic valve area
AVN
atrioventricular node
AVNRT
atrioventricular nodal re-entrant tachycardia
AVP
arginine vasopressin
AVSD
atrioventricular septal defect
BAV
bicuspid aortic valve
BB
bundle branch/es
BIMA
bilateral internal mammary artery
BMP
bone morphogenetic protein
BNP
brain natriuretic peptide
BOLD
blood oxygen level dependent
BP
blood pressure
BPEG
British Pacing and Electrophysiology Group
bpm
beats per minute
BRS
baroreflex sensitivity
BrS
Brugada syndrome
BSA
body surface area
BUN
blood urea nitrogen
CABG
coronary artery bypass graft
CACS
coronary artery calcium scoring
CAD
coronary artery disease
CAM
cell adhesion molecule
CAPD
continuous ambulatory peritoneal dialysis
CAT
common arterial trunk
CBT
cognitive behavioural therapy
CCR
comprehensive cardiac rehabilitation
CCUS
complete or comprehensive compression ultrasound
CEA
carcinoembryonic antigen or carotid endarterectomy
CETP
cholesteryl ester transfer protein
CFR
coronary flow reserve
CHD
coronary heart disease
CHF
chronic heart failure
CI
cardiac index or confidence interval
CK
creatine kinase
CKD
chronic kidney disease
CMR
cardiac magnetic resonance
CO
cardiac output
COX
cyclo-oxygenase
CPET
cardiopulmonary exercise testing
CPK
creatine phosphokinase
CPR
cardiopulmonary resuscitation
CPVT
catecholaminergic polymorphic ventricular tachycardia
CR
cardiac rehabilitation
CRF
conventional risk factor
CRT
cardiac resynchronization therapy
cSNRT
corrected sinus node recovery time
CTPA
computed tomography pulmonary angiography
CTPH
chronic thromboembolic pulmonary hypertension
CUS
compression ultrasound
CV
cardiovascular
CVD
cardiovascular disease
CVM
cardiovascular mortality
CW
continuous-wave
CYP
cytochrome P450
DAG
dystrophin-associated glycoprotein
DCM
dilated cardiomyopathy
DES
drug-eluting stent
DLCO
diffusion capacity for carbon monoxide
DSA
digital subtraction angiography
DSE
dobutamine stress echocardiography
DTI
direct thrombin inhibitor
DVT
deep vein thrombosis
EASD
European Association for the Study of Diabetes or electronic article surveillance
EBCT
electron-beam computed tomography
EBM
evidence-based medicine
ECG
electrocardiogram
ED
end-diastolic or Emergency Department
EDMD
Emery–Dreyfuss muscular dystrophy
EDV
end-diastolic volume
EEG
electroencephalogram
EEL
external elastic lamina
EEM
external elastic membrane
EF
ejection fraction
EHRA
European Heart Rhythm Association
ELISA
enzyme-linked immunosorbent assay
EMI
electromagnetic interference
eNOS
endothelial nitric oxide synthase
EPI
echo-planar imaging
EPO
erythropoietin
ER
European Region
ERO
effective regurgitant orifice
ES
end-systole or effect size
ESC
European Society of Cardiology
ESH
European Society of Hypertension
ET
endothelin
EU
Eustachian valve or European Union
FDCM
familial dilated cardiomyopathy
FEV1
forced expiratory volume at 1 second
FFR
fractional flow reserve
FH
familial hypercholesterolaemia
FLAIR
fluid attenuated inversion recovery
FLASH
fast low angle shot
FPG
fasting plasma glucose
FXaI
factor Xa inhibitor
GFR
glomerular filtration rate
GIK
glucose–insulin–potassium
GORD
gastro-oesophageal reflux disease
GUCH
grown-up congenital heart
GWAS
genome-wide association study
HB
His bundle
Hb
haemoglobin
HBE
His bundle electrogram
HCM
hypertrophic cardiomyopathy
HCTZ
hydrochlorothiazide
HDL
high-density lipoprotein
HELLP
haemolysis elevated liver enzymes low platelets
HES
hypereosinophilic syndrome
HF-PEF
heart failure with preserved left ventricular ejection fraction
HHT
hereditary haemorrhagic telangiectasia
HIPA
heparin-induced platelet activation
HIT
heparin-induced thrombocytopenia
HIV
human immunodeficiency virus
HLHS
hypoplastic left heart syndrome
HMG-CoA
5-hydroxy-3-methylglutaryl-coenzyme A
HPA
hypothalamus–pituitary–adrenal
HR
hazard ratio
HRQL
health-related quality of life
HRV
heart rate variability
HV
His–ventricular
ICA
internal carotid artery
ICD
implantable cardioverter defibrillator
IEL
internal elastic lamina
IFG
impaired fasting glucose
IGT
impaired glucose tolerance
IHD
ischaemic heart disease
IMR
index of microvascular resistance
INR
international normalized ratio
IPAH
idiopathic pulmonary arterial hypertension
IPT
interpersonal therapy
ISH
International Society of Hypertension
ITT
intention to treat
IV
intravenous
IVUS
intravascular ultrasound
JLN
Jervell and Lange–Nielsen [syndrome]
JVP
jugular venous pulse
K/DOQI
Kidney Disease Outcome Quality Initiative
KCCQ
Kansas City Cardiomyopathy Questionnaire
LA
left atrium/atrial
LAA
left atrial appendage
LAD
left anterior descending
LBB
left bundle branch
LBBB
left bundle branch block
LCA
left coronary artery
LCSD
left cardiac sympathetic denervation
LCX
left circumflex coronary artery
LDL
low-density lipoprotein
LDL-C
low-density lipoprotein cholesterol
LGE
late gadolinium enhancement
LGMD
limb girdle muscular dystrophy
LIMA
left internal mammary artery
LMWH
low-molecular-weight heparin
LOE
level of evidence
LQTS
long QT syndrome
LV
left ventricle/ventricular
LVAD
left ventricular assist device
LVEDP
left ventricular filling pressure
LVEF
left ventricular ejection fraction
LVH
left ventricular hypertrophy
LVM
left ventricular mass
LVNC
left ventricular non-compaction
LVOT
left ventricular outflow tract
MA
mitral annulus
MAPCA
major aortic pulmonary collateral artery
MAPK
mitogen-activated protein kinase
MAS
multiple system atrophy
MBM
mechanism-based medicine
mcg
microgram
MDRD
Modification of Diet in Renal Disease
MDTD
maximum daily therapeutic dose
MFS
Marfan syndrome
MHC
major histocompatibility complex
MI
myocardial infarction
MIBG
meta-iodobenzylguanidine
MMP
matrix metalloproteinase
MPa
megapascal
MPA
main pulmonary artery
MPS
myocardial perfusion scintigraphy
MR
magnetic resonance
MS
metabolic syndrome
MSCT
multislice computed tomography
MTWA
microvolt T-wave alternans
MV
mitral valve
MVA
mitral valve area
MVP
mitral valve prolapse
n-3 PUFA
omega-3 polyunsaturated fatty acid
NASPE
North American Society of Pacing and Electrophysiology
NFMI
non-fatal myocardial infarction
NFS
nephrogenic systemic fibrosis
NGAL
neutrophil gelatinase-associated lipocalin
NHLBI
National Heart, Lung, and Blood Institute
NIDDK
National Institute of Diabetes and Digestive and Kidney Diseases
NM
nuclear myocardial
NNH
number needed to harm
NNT
number needed to treat
NO
nitric oxide
NOS
nitric oxide synthase
NRT
nicotine replacement therapy
NSAID
non-steroidal anti-inflammatory drug
NSTE-ACS
non-ST-elevated acute coronary syndrome
NSVT
non-sustained ventricular tachycardia
NT-proBNP
N-terminal prohormone brain natriuretic peptide
NYHA
New York Heart Association
OAC
oral anticoagulation therapy
OCT
optical coherence tomography
OFDI
optical frequency domain imaging
OGTT
oral glucose tolerance test
OH
orthostatic hypotension
OR
odds ratio
PA
pulmonary artery
PAC
premature atrial contraction
PaCO2
arterial carbon dioxide tension
PAD
peripheral arterial disease
PAF
pure autonomic failure
PAH
pulmonary arterial hypertension
PAI
plasminogen activator inhibitor
PaO2
arterial oxygen tension
PAP
pulmonary artery pressure
PAR
pulmonary arteriolar resistance
PASP
pulmonary artery systolic pressure
PAV
percutaneous aortic valvuloplasty
PCCD
progressive cardiac conduction defect
PCI
percutaneous coronary intervention
PCM
physical counter-pressure manoeuvre
PCR
polymerase chain reaction
PCW
pulmonary wedge pressure
PDA
posterior descending artery
PDE
phosphodiesterase
PDE-5
phosphodiesterase type 5
PE
pulmonary embolism
PES
programmed electrical stimulation
PET
positron emission tomography
PF
physical functioning
PFHB
progressive familial heart block
PH
pulmonary hypertension
PHQ
Patient Health Questionnaire
PI
posteroinferior fascicle
PIC
pro-inflammatory cytokine
PIH
pregnancy-induced hypertension
PISA
proximal isovelocity surface area
PKC
protein kinase C
PMC
percutaneous mitral balloon commissurotomy
PMI
point of maximal impulse or perioperative myocardial infarction
PMR
progressive muscle relaxation
PND
paroxysmal nocturnal dyspnoea
PO
per os [by mouth]
POTS
postural orthostatic tachycardia syndrome
PPCM
peripartum cardiomyopathy
PPHN
persistent pulmonary hypertension of the neonates
PSS
post-systolic shortening
PTA
percutaneous transluminal angioplasty
PTCA
percutaneous transluminal coronary angioplasty
PTEA
pulmonary thromboendarterectomy
PTFE
polytetrafluoretilene
PTH
parathyroid hormone
PTS
post-thrombotic syndrome
PTSD
post-traumatic stress disorder
PV
pressure–volume
PVD
peripheral vascular disease
PVR
pulmonary vascular resistance
PW
pulsed-wave
PWP
pulmonary wedge pressure
QTL
quantitative trait loci
RA
right atrium
RAA
renin–angiotensin–aldosterone
RAAS
renin–angiotensin–aldosterone system
RAS
renin–angiotensin system
RBB
right bundle branch
RBBB
right bundle branch block
RCA
right coronary artery
ROC
receiver operating characteristic
ROS
reactive oxygen species
RR
relative risk
RRR
relative risk reduction
rtPA
recombinant tissue plasminogen activator
RV
right ventricle/ventricular
RVA
right ventricular apex
RVOT
right ventricular outflow tract
SAECG
signal-averaged electrocardiogram
SAM
systolic anterior motion
SAQ
Seattle Angina Questionnaire
SBP
systolic blood pressure
SCD
sudden cardiac death
SES
sirolimus-eluting stents or socio-economic status
SF-36
Short Form Health Survey 36
SMR
standardized mortality ratio
SNP
single nucleotide polymorphism
SPECT
single photon emission computed tomography
SQTS
short QT syndrome
SR
sustained release
SR
sarcoplasmic reticulum
SSFP
steady state with free precession
SSI
steady state inactivation
SSRI
selective serotonin reuptake inhibitor
SSS
sick sinus syndrome
STEMI
ST-elevation myocardial infarction
STS
Society of Thoracic Surgeons
SV
stroke volume
SVI
stroke volume index
SVR
systemic vascular resistance
SVT
supraventricular tachycardia
TAPVC
total anomalous pulmonary venous connection
TAVI
transcatheter aortic valve implantation
TC
Takotsubo cardiomyopathy
TCA
tricyclic antidepressant
TCMP
tachycardia-induced cardiomyopathy
TCPC
total cavopulmonary connection
TDI
tissue Doppler imaging
TdP
Torsade de pointes
TE
echo time
TGA
transposition of the great arteries
TIA
transient ischaemic attack
TIMI
thrombolysis in myocardial infarction
T-LOC
transient loss of consciousness
TOE
transoesophageal echocardiography
tPA
tissue plasminogen activator
TPG
transpulmonary pressure gradient
TPR
total pulmonary resistance
TR
tricuspid regurgitation
TS
tricuspid stenosis
TSH
thyroid-stimulating hormone
TTE
transthoracic echocardiography
TTM
trans-telephonic monitoring
TWA
T-wave alternans
UFH
unfractionated heparin
VD
volume of distribution
VEGF
vascular endothelial growth factor
VF
ventricular fibrillation
VHD
valvular heart disease
VKA
vitamin K antagonist
VLDL
very-low-density lipoprotein
VPB
ventricular premature beat
VSD
ventricular septal defect
VT
ventricular tachycardia
VTE
venous thromboembolism
VVS
vasovagal syncope
WHO
World Health Organization
WPW
Wolff–Parkinson–White syndrome






Contents
Front Matter
Foreword Preface Contributors Reviewers Acknowledgement to first edition contributors Symbols and abbreviations
CHAPTER 1 The Cardiovascular History and Physical Examination 
Roger Hall and Iain Simpson
Summary Introduction History Examination Conclusion Key points Personal perspective Online resources Further reading References
CHAPTER 2 The Electrocardiogram 
Francisco G. Cosío, José Palacios, Agustín Pastor, and Ambrosio Núñez
Summary Introduction Recording the electrical activity of the heart Chamber enlargement/hypertrophy Ischaemia and infarction Conduction disturbances Pre-excitation (also see Formula Chapter 28) Primary repolarization disturbances Pericarditis and pericardial effusion An approach to ECG reading An approach to arrhythmia diagnosis Stress ECG Ambulatory ECG monitoring Implantable loop recorder Computer analysis of the ECG Personal perspective Online resources Further reading References
CHAPTER 3 Choice of Imaging Techniques 
Joanne D. Schuijf, Nico R. Van de Veire, Ernst E. van der Wall, and Jeroen J. Bax
Summary Introduction The patient with stable chest pain presenting at the outpatient clinic The patient with chronic heart failure Personal perspective Additional online material Further reading References
CHAPTER 4 Cardiac Ultrasound 
Frank A. Flachskampf, Jens-Uwe Voigt, and Werner G. Daniel
Summary Physical and technical principles of echocardiography Specific cardiovascular structures Key echocardiographic features of frequent diseases and clinical scenarios Personal perspective Additional online material Further reading References
CHAPTER 5 Cardiovascular Magnetic Resonance 
Dudley J. Pennell, Udo P. Sechtem, Sanjay Prasad, and Frank E. Rademakers
Summary Basic principles Volumes and function Myocardial infarction and viability Ischaemia detection Acute coronary syndromes (also see Formula Chapter 16) Coronary arteries Vessel wall Cardiomyopathy Valvular heart disease Congenital heart disease (also see Formula Chapter 10) Great vessels (also see Formula Chapter 31) Pericardium (also see Formula Chapter 19) Tumours and masses Personal perspective Further reading References
CHAPTER 6 Cardiovascular Computed Tomography 
Pim J. de Feyter, Stephan Achenbach, and Koen Nieman
Summary Introduction Basics of computed tomography Clinical applications of cardiac computed tomography Personal perspective Additional online material Further reading References
CHAPTER 7 Nuclear Cardiology 
Philipp A. Kaufmann, Paolo G. Camici, and S. Richard Underwood
Summary Diagnosis of coronary artery disease Heart failure: myocardial viability and hibernation Microvascular disease (Formula Chapter 17) Personal perspective Further reading References
CHAPTER 8 Invasive Imaging and Haemodynamics 
Carlo Di Mario, Guy R. Heyndrickx, Francesco Prati, and Nico H.J. Pijls
Summary Introduction Percutaneous techniques of cardiac catheterization Haemodynamic measurements during cardiac catheterization Invasive imaging techniques and coronary morphology Functional assessment of the coronary circulation Personal perspective Further reading References
CHAPTER 9 Genetics of Cardiovascular Diseases 
Silvia G. Priori, Carlo Napolitano, Steve E. Humphries, and James Skipworth
Summary Mendelian monogenic human diseases: an overview Monogenic diseases with myocardial involvement Marfan syndrome Genetic disorders in the structurally normal heart Polygenic diseases: genetic aspects of coronary artery disease Hypertension (Formula Chapter 13) Personal perspective Online resources Further reading References
CHAPTER 10 Congenital Heart Disease in Children and Adults 
John E. Deanfield, Robert Yates, Folkert J. Meijboom, and Barbara J.M. Mulder
Summary Introduction Nomenclature Epidemiology and incidence Aetiology and prevention Fetal circulation Pathophysiology Investigation Management Grown-up congenital heart disease Common congenital cardiac malformations Personal perspective Online resources Additional online material Further reading References
CHAPTER 11 Clinical Pharmacology of Cardiovascular Drugs 
Faiez Zannad, Pascal Bousquet, and Laurent Monassier
Summary Basic concepts in clinical pharmacology Clinical trials and assessment of evidence Personal perspective Online resources Further reading References
CHAPTER 12 Prevention of Cardiovascular Disease 
Annika Rosengren, Joep Perk, and Jean Dallongeville
Summary Introduction Facts and figures about CVD in Europe Prevention strategies Population strategy Modifying CVD risk at the individual level High-risk strategy Secondary prevention Smoking Physical activity Blood pressure Nutrition Obesity and problems related to obesity Lipids Psychosocial factors Gender aspects in prevention Conclusion Personal perspective Online resources Further reading References
CHAPTER 13 Hypertension 
Sverre E. Kjeldsen, Tonje A. Aksnes, Robert H. Fagard, and Giuseppe Mancia
Summary Introduction Definition and classification of hypertension Diagnostic evaluation Therapeutic approach Personal perspective Online resources Further reading References
CHAPTER 14 Diabetes Mellitus and Metabolic Syndrome 
Francesco Cosentino, Lars Rydén, Pietro Francia, and Linda G. Mellbin
Summary Introduction Vascular disease risk factors: from pathophysiology to clinical management Clinical presentation and management of cardiovascular disease Selected issues The metabolic syndrome Personal perspective Further reading References
CHAPTER 15 Heart and Other Organs 
Frank Ruschitzka
Introduction
CHAPTER 16 Acute Coronary Syndromes 
Christian W. Hamm, Helge Möllmann, Jean-Pierre Bassand, and Frans van de Werf
Summary Introduction Incidence and prevalence of acute coronary syndromes General risk factors for acute coronary syndromes Pathophysiology of acute coronary syndromes The plaque Thrombotic response Development of myocardial infarction Diagnosis and risk stratification of acute coronary syndromes Treatment of non-ST-elevation acute coronary syndromes Treatment of ST-elevation acute coronary syndromes Personal perspective Online resources Further reading References
CHAPTER 17 Chronic Ischaemic Heart Disease 
Filippo Crea, Paolo G. Camici, Raffaele De Caterina, and Gaetano A. Lanza
Summary Introduction The coronary circulation Myocardial ischaemia Coronary collateral circulation Epidemiology of chronic ischaemic heart disease Assessment of angina pectoris Stable angina: diagnosis Stable angina: risk stratification Chronic stable angina: medical treatment Chronic stable angina: myocardial revascularization Other clinical manifestations of chronic ischaemic heart disease Personal perspective Additional online material Further reading References
CHAPTER 18 Myocardial Disease 
Otto M. Hess, William McKenna, and Heinz-Peter Schultheiss
Summary Definition and classification Primary myocardial disease (cardiomyopathies) Secondary myocardial diseases Personal perspective Further reading References
CHAPTER 19 Pericardial Disease 
Jordi Soler-Soler and Jaume Sagristà-Sauleda
Summary Introduction Acute pericardial syndromes Pericardial effusion Constrictive pericarditis Specific types of pericardial disease Personal perspective Additional online material Further reading References
CHAPTER 20 Tumours of the Heart 
Gaetano Thiene, Marialuisa Valente, Massimo Lombardi, and Cristina Basso
Summary Introduction Epidemiology, classification, and nomenclature Clinical presentation Diagnosis through interdisciplinary collaboration Benign tumours Benign tumours of paediatric age Other benign tumours Malignant tumours of the heart Malignant tumours of the pericardium Cardiac metastases Chemotherapy, radiotherapy, and cardiotoxicity in malignant cardiac neoplasms Non-neoplastic masses Surgical treatment Personal perspective Further reading References
CHAPTER 21 Valvular Heart Disease 
Alec Vahanian, Bernard Iung, Luc Piérard, Robert Dion, and John Pepper
Summary Introduction Patient evaluation Aortic stenosis Aortic regurgitation Mitral stenosis Mitral regurgitation Tricuspid valve disease Prosthetic valve surgery Personal perspective Online resources Additional online material Further reading References
CHAPTER 22 Infective Endocarditis 
Werner G. Daniel and Frank A. Flachskampf
Summary Definition Epidemiology Pathology and pathophysiology Risk factors Causative pathogens Symptoms and signs Diagnosis Echocardiographic signs of infective endocarditis Problems in the diagnosis of infective endocarditis Prosthetic valve endocarditis Infective endocarditis in addicts of intravenous drugs Therapy Indications, timing, and type of surgery Anticoagulation Prognosis Prophylaxis and prevention Personal perspective Additional online material Further reading References
CHAPTER 23 Heart Failure 
John McMurray, Mark Petrie, Karl Swedberg, Michel Komajda, Stefan Anker, and Roy Gardner
Summary Introduction Epidemiology Aetiology: causes of heart failure Comorbidity Pathophysiology Cardiac responses to ventricular injury and reduced stroke volume Diagnosis: symptoms, signs, and investigations Treatment Heart failure with a low left ventricular ejection fraction Organization of care Education Treatment considerations related to comorbidity Devices and surgery Surgery Heart failure with preserved left ventricular ejection fraction Heart failure due to valvular heart disease Heart failure due to dilated cardiomyopathy Heart failure due to hypertrophic cardiomyopathy Acute heart failure and pulmonary oedema End-of-life considerations Acknowledgement Personal perspective Online resources Further reading References
CHAPTER 24 Pulmonary Hypertension 
Nazzareno Galiè and Alessandra Manes
Summary Definition and classification of pulmonary hypertension Pathology and pathobiology of pulmonary hypertension Genetics and epidemiology Pulmonary arterial hypertension (Group 1) Pulmonary hypertension associated with left heart disease (Group 2) Pulmonary hypertension associated with lung diseases (Group 3) Chronic thromboembolic pulmonary hypertension (Group 4) Personal perspective Additional online material Further reading References
CHAPTER 25 Cardiac Rehabilitation 
Stephan Gielen, Alessandro Mezzani, Rainer Hambrecht, and Hugo Saner
Summary Definition of cardiac rehabilitation within preventive cardiology Exercise testing in cardiovascular medicine Physical activity, physical fitness, and cardiovascular diseases Exercise intolerance in cardiovascular diseases Exercise-based interventions in cardiac rehabilitation and secondary prevention Comprehensive rehabilitation and risk factor management Personal perspective Further reading References
CHAPTER 26 Syncope 
Michele Brignole, Jean-Jacques Blanc, Richard Sutton, and Angel Moya
Summary Definition Epidemiology Classification and pathophysiology Evaluation of a patient with T-LOC Diagnostic tests Treatment Personal perspective Further reading References
CHAPTER 27 Bradycardia 
Panos E. Vardas, Hercules E. Mavrakis, and William D. Toff
Summary Introduction Anatomy and physiology of the basic rhythm of the heart Definition of bradycardia Causes of bradycardia Clinical and electrocardiographic findings in patients with bradycardia Treatment of bradycardia Personal perspective Further reading References
CHAPTER 28 Supraventricular Tachycardias 
Jerónimo Farré, Hein J.J. Wellens, José M. Rubio, and Juan Benezet
Summary Introduction Atrial and atrioventricular junctional extrasystoles Supraventricular tachycardia Atrial tachycardia Atrial flutter Atrioventricular nodal reciprocating tachycardia Accessory pathways, pre-excitation syndromes, and their tachycardias Wolff–Parkinson–White syndrome Pre-excitation due to ‘Mahaim physiology’ Concealed accessory pathways Permanent junctional reciprocating tachycardia Other non-paroxysmal SVT Personal perspective Further reading References
CHAPTER 29 Atrial Fibrillation 
A. John Camm, Paulus Kirchhof, Gregory Y.H. Lip, Irena Savelieva, and Sabine Ernst
Summary Epidemiology Pathophysiological changes that can cause atrial fibrillation Initial evaluation of patients with atrial fibrillation Antithrombotic therapy for atrial fibrillation Pharmacological therapy Electrical cardioversion Implantable pacemakers and defibrillators Catheter ablation of the atrioventricular node Ablation of atrial fibrillation Personal perspective Online resources Additional online material Further reading References
CHAPTER 30 Ventricular Tachycardia and Sudden Cardiac Death 
Lars Eckardt, Günter Breithardt, and Stefan Hohnloser
Summary Introduction Definitions Electrocardiographic diagnosis of ventricular tachycardia Electrophysiological mechanisms of ventricular tachycardia Ventricular tachycardia: clinical presentation Broad QRS complex tachycardia: clinical approach Risk stratification Therapy of ventricular tachycardias in patients with structural heart disease Catheter ablation or surgical treatment of ventricular tachyarrhythmias Other cardiomyopathic conditions Drug-induced ventricular tachyarrhythmias Resuscitation Conclusion Personal perspective Online resources Further reading References
CHAPTER 31 Diseases of the Aorta and Trauma to the Aorta and the Heart 
Christoph A. Nienaber, Ibrahim Akin, Raimund Erbel, and Axel Haverich
Summary Aneurysms of the thoracic aorta Dissection of the thoracic aorta Aortitis Aortic atheromatous disease: thrombotic or cholesterol emboli Traumatic rupture of the aorta Trauma to the heart Personal perspective Further reading References
CHAPTER 32 Sports and Heart Disease 
Domenico Corrado, Cristina Basso, Antonio Pelliccia, and Gaetano Thiene
Summary Introduction Classification of sports The athlete’s heart Epidemiology of sudden death in the athlete Prevention of sudden death by preparticipation screening Interpretation of the athlete’s ECG Management of athletes with cardiovascular diseases Automatic external defibrillator programme Personal perspective Further reading References
CHAPTER 33 Pregnancy and Heart Disease 
Patrizia Presbitero, Giacomo G. Boccuzzi, Christianne J.M. Groot, and Jolien W. Roos-Hesselink
Summary Cardiovascular adaptations during normal pregnancy Haemodynamic changes during pregnancy Cardiac evaluation in normal pregnancy Assessment of heart disease in pregnancy Maternal low-risk conditions Maternal high-risk conditions Congenital heart disease and pregnancy Fetal high-risk conditions Specific conditions Cardiovascular treatment during pregnancy Personal perspective Online resources References
CHAPTER 34 Non-cardiac Surgery in Cardiac Patients 
Sanne Hoeks and Don Poldermans
Summary Introduction Pathophysiology of myocardial infarction Risk stratification Non-invasive testing Invasive testing Medical therapy Revascularization Conclusion Personal perspective Further reading References
CHAPTER 35 Psychological Factors and Heart Disease 
Susanne S. Pedersen, Nina Kupper, and Johan Denollet
Summary Introduction Psychological impact of heart disease Psychological risk factors for poor prognosis Mechanisms linking psychological factors to adverse prognosis Pharmacological and behavioural interventions Clinical implications Conclusion Personal perspective Additional online material Further reading References
CHAPTER 36 Peripheral Arterial Occlusive Disease 
Alberto Cremonesi, Nicolas Diehm, Andrea Stella, Mauro Gargiulo, Gianluca Faggioli, Estêvão Carvalho de Campos Martins, and Fausto Castriota
Summary Peripheral arterial disease Cerebral vascular disease Renal artery stenosis Personal perspective Acknowledgement Additional online material Further reading References
CHAPTER 37 Venous Thromboembolism 
Sebastian M. Schellong, Henri Bounameaux, and Harry R. Büller
Summary Natural history Diagnosis Treatment Personal perspective Further reading References
CHAPTER 38 Occupational and Regulatory Aspects of Heart Disease 
Demosthenes G. Katritsis and Michael M. Webb-Peploe
Summary Occupational risk factors for heart disease Regulations concerning individual risk and public safety Personal perspective Acknowledgement Online resources Further reading References
Disclaimer

Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up to date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work.

Oxford Journals: latest research
Oxford Journals: related titles
  • European Heart Journal cover image
Oxford Medical Handbooks: related titles
  • Oxford Handbook of Cardiology
  • Oxford Handbook of Anaesthesia
  • Oxford Handbook of Clinical Medicine