Contents
- Front Matter
- Foreword Preface Contributors Reviewers Acknowledgement to first edition contributors Symbols and abbreviations
- CHAPTER 1 The Cardiovascular History and Physical Examination
- Summary Introduction History Examination Conclusion Key points Personal perspective Online resources Further reading References
- CHAPTER 2 The Electrocardiogram
-
Summary
Introduction
Recording the electrical activity of the heart
Chamber enlargement/hypertrophy
Ischaemia and infarction
Conduction disturbances
Pre-excitation (also see
Chapter 28)
Primary repolarization disturbances
Pericarditis and pericardial effusion
An approach to ECG reading
An approach to arrhythmia diagnosis
Stress ECG
Ambulatory ECG monitoring
Implantable loop recorder
Computer analysis of the ECG
Personal perspective
Online resources
Further reading
References
- CHAPTER 3 Choice of Imaging Techniques
- Summary Introduction The patient with stable chest pain presenting at the outpatient clinic The patient with chronic heart failure Personal perspective Additional online material Further reading References
- CHAPTER 4 Cardiac Ultrasound
- Summary Physical and technical principles of echocardiography Specific cardiovascular structures Key echocardiographic features of frequent diseases and clinical scenarios Personal perspective Additional online material Further reading References
- CHAPTER 5 Cardiovascular Magnetic Resonance
-
Summary
Basic principles
Volumes and function
Myocardial infarction and viability
Ischaemia detection
Acute coronary syndromes (also see
Chapter 16)
Coronary arteries
Vessel wall
Cardiomyopathy
Valvular heart disease
Congenital heart disease (also see
Chapter 10)
Great vessels (also see
Chapter 31)
Pericardium (also see
Chapter 19)
Tumours and masses
Personal perspective
Further reading
References
- CHAPTER 6 Cardiovascular Computed Tomography
- Summary Introduction Basics of computed tomography Clinical applications of cardiac computed tomography Personal perspective Additional online material Further reading References
- CHAPTER 7 Nuclear Cardiology
-
Summary
Diagnosis of coronary artery disease
Heart failure: myocardial viability and hibernation
Microvascular disease (
Chapter 17)
Personal perspective
Further reading
References
- CHAPTER 8 Invasive Imaging and Haemodynamics
- Summary Introduction Percutaneous techniques of cardiac catheterization Haemodynamic measurements during cardiac catheterization Invasive imaging techniques and coronary morphology Functional assessment of the coronary circulation Personal perspective Further reading References
- CHAPTER 9 Genetics of Cardiovascular Diseases
-
Summary
Mendelian monogenic human diseases: an overview
Monogenic diseases with myocardial involvement
Marfan syndrome
Genetic disorders in the structurally normal heart
Polygenic diseases: genetic aspects of coronary artery disease
Hypertension (
Chapter 13)
Personal perspective
Online resources
Further reading
References
- CHAPTER 10 Congenital Heart Disease in Children and Adults
- Summary Introduction Nomenclature Epidemiology and incidence Aetiology and prevention Fetal circulation Pathophysiology Investigation Management Grown-up congenital heart disease Common congenital cardiac malformations Personal perspective Online resources Additional online material Further reading References
- CHAPTER 11 Clinical Pharmacology of Cardiovascular Drugs
- Summary Basic concepts in clinical pharmacology Clinical trials and assessment of evidence Personal perspective Online resources Further reading References
- CHAPTER 12 Prevention of Cardiovascular Disease
- Summary Introduction Facts and figures about CVD in Europe Prevention strategies Population strategy Modifying CVD risk at the individual level High-risk strategy Secondary prevention Smoking Physical activity Blood pressure Nutrition Obesity and problems related to obesity Lipids Psychosocial factors Gender aspects in prevention Conclusion Personal perspective Online resources Further reading References
- CHAPTER 13 Hypertension
- Summary Introduction Definition and classification of hypertension Diagnostic evaluation Therapeutic approach Personal perspective Online resources Further reading References
- CHAPTER 14 Diabetes Mellitus and Metabolic Syndrome
- Summary Introduction Vascular disease risk factors: from pathophysiology to clinical management Clinical presentation and management of cardiovascular disease Selected issues The metabolic syndrome Personal perspective Further reading References
- Chapter 15a The Heart and the Brain
- CHAPTER 15a The Heart and the Brain
- Summary Pathophysiology of acute ischaemic stroke and diagnostic procedures Characteristics of cardioembolic stroke Treatment of acute ischaemic stroke Cryptogenic stroke and patent foramen ovale Secondary stroke prevention in patients with atrial fibrillation Secondary stroke prevention with antiplatelet drugs Secondary stroke prevention and hypertension Secondary stroke prevention in patients with coronary heart disease Secondary stroke prevention in patients with significant stenosis of brain-supplying arteries Secondary stroke prevention in heart failure Personal perspective Further reading References
- Chapter 15b Cardiovascular Problems in Chronic Kidney Disease
- CHAPTER 15b Cardiovascular Problems in Chronic Kidney Disease
- Summary Chronic kidney disease as a cardiovascular risk factor Chronic kidney disease and cardiovascular mortality Causes of death and underlying pathology in end-stage renal disease What clinical examinations are useful or necessary in the patient with end-stage renal disease? Radiocontrast nephropathy Acute reactions and nephrogenic skin fibrosis after gadolinium Interventions to reduce the cardiovascular risk Diuretic therapy Personal perspective Further reading References
- Chapter 15c Erectile Dysfunction
- CHAPTER 15c Erectile Dysfunction
- Summary Introduction Cardiovascular response to sex Cardiac risk Assessing the risk of sex activity Erectile dysfunction and the cardiac patient Cardiovascular risk factors Erectile dysfunction as a predictor of occult coronary artery disease Treating erectile dysfunction in men with cardiovascular disease Drug therapy Non-drug therapy Quick guide to specific cardiac conditions and sex Conclusion Personal perspective Further reading References
- CHAPTER 16 Acute Coronary Syndromes
- Summary Introduction Incidence and prevalence of acute coronary syndromes General risk factors for acute coronary syndromes Pathophysiology of acute coronary syndromes The plaque Thrombotic response Development of myocardial infarction Diagnosis and risk stratification of acute coronary syndromes Treatment of non-ST-elevation acute coronary syndromes Treatment of ST-elevation acute coronary syndromes Personal perspective Online resources Further reading References
- CHAPTER 17 Chronic Ischaemic Heart Disease
- Summary Introduction The coronary circulation Myocardial ischaemia Coronary collateral circulation Epidemiology of chronic ischaemic heart disease Assessment of angina pectoris Stable angina: diagnosis Stable angina: risk stratification Chronic stable angina: medical treatment Chronic stable angina: myocardial revascularization Other clinical manifestations of chronic ischaemic heart disease Personal perspective Additional online material Further reading References
- CHAPTER 18 Myocardial Disease
- Summary Definition and classification Primary myocardial disease (cardiomyopathies) Secondary myocardial diseases Personal perspective Further reading References
- CHAPTER 19 Pericardial Disease
- Summary Introduction Acute pericardial syndromes Pericardial effusion Constrictive pericarditis Specific types of pericardial disease Personal perspective Additional online material Further reading References
- CHAPTER 20 Tumours of the Heart
- Summary Introduction Epidemiology, classification, and nomenclature Clinical presentation Diagnosis through interdisciplinary collaboration Benign tumours Benign tumours of paediatric age Other benign tumours Malignant tumours of the heart Malignant tumours of the pericardium Cardiac metastases Chemotherapy, radiotherapy, and cardiotoxicity in malignant cardiac neoplasms Non-neoplastic masses Surgical treatment Personal perspective Further reading References
- CHAPTER 21 Valvular Heart Disease
- Summary Introduction Patient evaluation Aortic stenosis Aortic regurgitation Mitral stenosis Mitral regurgitation Tricuspid valve disease Prosthetic valve surgery Personal perspective Online resources Additional online material Further reading References
- CHAPTER 22 Infective Endocarditis
- Summary Definition Epidemiology Pathology and pathophysiology Risk factors Causative pathogens Symptoms and signs Diagnosis Echocardiographic signs of infective endocarditis Problems in the diagnosis of infective endocarditis Prosthetic valve endocarditis Infective endocarditis in addicts of intravenous drugs Therapy Indications, timing, and type of surgery Anticoagulation Prognosis Prophylaxis and prevention Personal perspective Additional online material Further reading References
- CHAPTER 23 Heart Failure
- Summary Introduction Epidemiology Aetiology: causes of heart failure Comorbidity Pathophysiology Cardiac responses to ventricular injury and reduced stroke volume Diagnosis: symptoms, signs, and investigations Treatment Heart failure with a low left ventricular ejection fraction Organization of care Education Treatment considerations related to comorbidity Devices and surgery Surgery Heart failure with preserved left ventricular ejection fraction Heart failure due to valvular heart disease Heart failure due to dilated cardiomyopathy Heart failure due to hypertrophic cardiomyopathy Acute heart failure and pulmonary oedema End-of-life considerations Acknowledgement Personal perspective Online resources Further reading References
- CHAPTER 24 Pulmonary Hypertension
- Summary Definition and classification of pulmonary hypertension Pathology and pathobiology of pulmonary hypertension Genetics and epidemiology Pulmonary arterial hypertension (Group 1) Pulmonary hypertension associated with left heart disease (Group 2) Pulmonary hypertension associated with lung diseases (Group 3) Chronic thromboembolic pulmonary hypertension (Group 4) Personal perspective Additional online material Further reading References
- CHAPTER 25 Cardiac Rehabilitation
- Summary Definition of cardiac rehabilitation within preventive cardiology Exercise testing in cardiovascular medicine Physical activity, physical fitness, and cardiovascular diseases Exercise intolerance in cardiovascular diseases Exercise-based interventions in cardiac rehabilitation and secondary prevention Comprehensive rehabilitation and risk factor management Personal perspective Further reading References
- CHAPTER 26 Syncope
- Summary Definition Epidemiology Classification and pathophysiology Evaluation of a patient with T-LOC Diagnostic tests Treatment Personal perspective Further reading References
- CHAPTER 27 Bradycardia
- Summary Introduction Anatomy and physiology of the basic rhythm of the heart Definition of bradycardia Causes of bradycardia Clinical and electrocardiographic findings in patients with bradycardia Treatment of bradycardia Personal perspective Further reading References
- CHAPTER 28 Supraventricular Tachycardias
- Summary Introduction Atrial and atrioventricular junctional extrasystoles Supraventricular tachycardia Atrial tachycardia Atrial flutter Atrioventricular nodal reciprocating tachycardia Accessory pathways, pre-excitation syndromes, and their tachycardias Wolff–Parkinson–White syndrome Pre-excitation due to ‘Mahaim physiology’ Concealed accessory pathways Permanent junctional reciprocating tachycardia Other non-paroxysmal SVT Personal perspective Further reading References
- CHAPTER 29 Atrial Fibrillation
- Summary Epidemiology Pathophysiological changes that can cause atrial fibrillation Initial evaluation of patients with atrial fibrillation Antithrombotic therapy for atrial fibrillation Pharmacological therapy Electrical cardioversion Implantable pacemakers and defibrillators Catheter ablation of the atrioventricular node Ablation of atrial fibrillation Personal perspective Online resources Additional online material Further reading References
- CHAPTER 30 Ventricular Tachycardia and Sudden Cardiac Death
- Summary Introduction Definitions Electrocardiographic diagnosis of ventricular tachycardia Electrophysiological mechanisms of ventricular tachycardia Ventricular tachycardia: clinical presentation Broad QRS complex tachycardia: clinical approach Risk stratification Therapy of ventricular tachycardias in patients with structural heart disease Catheter ablation or surgical treatment of ventricular tachyarrhythmias Other cardiomyopathic conditions Drug-induced ventricular tachyarrhythmias Resuscitation Conclusion Personal perspective Online resources Further reading References
- CHAPTER 31 Diseases of the Aorta and Trauma to the Aorta and the Heart
- Summary Aneurysms of the thoracic aorta Dissection of the thoracic aorta Aortitis Aortic atheromatous disease: thrombotic or cholesterol emboli Traumatic rupture of the aorta Trauma to the heart Personal perspective Further reading References
- CHAPTER 32 Sports and Heart Disease
- Summary Introduction Classification of sports The athlete’s heart Epidemiology of sudden death in the athlete Prevention of sudden death by preparticipation screening Interpretation of the athlete’s ECG Management of athletes with cardiovascular diseases Automatic external defibrillator programme Personal perspective Further reading References
- CHAPTER 33 Pregnancy and Heart Disease
- Summary Cardiovascular adaptations during normal pregnancy Haemodynamic changes during pregnancy Cardiac evaluation in normal pregnancy Assessment of heart disease in pregnancy Maternal low-risk conditions Maternal high-risk conditions Congenital heart disease and pregnancy Fetal high-risk conditions Specific conditions Cardiovascular treatment during pregnancy Personal perspective Online resources References
- CHAPTER 34 Non-cardiac Surgery in Cardiac Patients
- Summary Introduction Pathophysiology of myocardial infarction Risk stratification Non-invasive testing Invasive testing Medical therapy Revascularization Conclusion Personal perspective Further reading References
- CHAPTER 35 Psychological Factors and Heart Disease
- Summary Introduction Psychological impact of heart disease Psychological risk factors for poor prognosis Mechanisms linking psychological factors to adverse prognosis Pharmacological and behavioural interventions Clinical implications Conclusion Personal perspective Additional online material Further reading References
- CHAPTER 36 Peripheral Arterial Occlusive Disease
- Summary Peripheral arterial disease Cerebral vascular disease Renal artery stenosis Personal perspective Acknowledgement Additional online material Further reading References





